Course Title: Sustainable chemistry

Course supervisor:

• J. Peron

Goals: The aims of this course are (i) to remind the global scientific and economic context of climate and ecosystem changes induced by human activities, (ii) to identify some domains in which chemical research and technology can implement sustainable alternatives solutions, (ii) to provide an overview of the research themes that respond to the need for sustainable development and (iv) to link research article with sustainable development goals reported in reports from GIEC, ADEME or CCC (french convention citoyenne pour le climat).

Description: 

The reports from GIEC and ADEME are alerting on the important societal risks associated with climate change. Beside this aspect of the human fingerprint, the pollution of the environment gives rise to additional toxicological and epidemiological risks. Therefor rising part of the economy, industry and research implement sustainability in their policy or direct their activities in order to provide sustainable technologies. As a consequence, it is worth to provide education to the future chemist who should face this new challenge/constraint.

The course is composed of a lecture part (12h) illustrating the context of climate and ecosystem changes as well as some chemical research domain responding to sustainable development goals. Then during a second active learning part (6h), the student (group of 3-4) should on their own look for a research article reporting results that may have an impact for sustainable development. The students should present to peers (i) the scientific content and (ii) the sustainable development goal it is related to, based on reports of GIEC, ADEME, or CCC.

Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basis of sustainable development

Teaching methods and activities: Lectures (CM), Practical sessions (Article presentation)

Course Title: Scientific communication

Course supervisor:

• S. Zrig & A. Perrier

Goals: This course focuses on developing the essential professional skills necessary to thrive in the modern job market.

Description:  Students will develop proficiency in areas such as effective (scientific) communication, argumentation, teamwork, and problem-solving.  A significant focus will be placed on resume writing, cover letter composition, and interview preparation, enabling students to present themselves confidently and competitively to potential employers for Master internships and future professional opportunities.  Additionally, students will actively participate in real-world projects, either individually or in teams, under the guidance of mentors.  Upon completion of the course, students will have gained valuable experience in project management and presentation skills.

Key words: Résumé, cover letter and internship search and  personal interviews

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: none

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Chemistry and data sciences

Course supervisor:

• Eric Bremond & A. Perrier

Goals: The objective of this lecture is to learn how to use numerical tools for the treatment of chemical data or the analysis of problems belonging to physics and chemistry.

Description: The students will learn how to analyze and plot data, how to use graphical tools, numerical analysis and scientific programming. The first part of the course (lecture 8h) will be dedicated to the introduction of different concepts related to programming and more particularly those related to the Python language (variables, data types, input/output, conditions, loops, lists, open/ write files, functions, introduction to modules), and to the presentation of the statistical tools in use in chemistry from basics to the opening of AI world. The second part of the lecture will be dedicated to practicals (16h) with a series of hands-on problem. The students will particularly use the Numpy, Pandas et Matplotlib libraries to get familiar with the chemometric tools necessary for the statistical exploitation of experimental results. The following concepts will thus be addressed via examples based on analytical chemistry: basic statistics (median, standard deviation, variance, normal distribution, confidence interval, confidence limit), metrology (experimental errors, error propagation), estimation of variance components by analysis of variance (repeatability, reproducibility), calibration curves, statistical tests (Fisher, Student ), multivariate statistical methods in chemistry (multilinear regression, Principal Component Analysis (PCA), Principal Component Regression PCR).

Key words: Statistics Tools ; Chemometrics; Panda Library ; IA

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basis in Python Programming

Teaching methods and activities: Lectures (CM), lab sessions (TP)

Course Title: Molecule and surface characterization

Course supervisor:

• N. Giraud & C. Mangeney

Goals: Characterizing molecules, materials, and surfaces across various scales is crucial for understanding and optimizing them. Currently, spectroscopic tools are experiencing significant advancements, both in instrumentation and methodology. This course will focus on two main areas: nuclear magnetic resonance (NMR) and optical spectroscopic techniques, including UV-visible, fluorescence, IR, and Raman spectroscopies.

Description: The course will cover the use of these techniques from molecule analysis to surface characterization, integrating focuses on the development of optical microscopy techniques and surface-enhanced spectroscopies (SERS, SEIRA, metal-enhanced fluorescence). It aims to introduce students to these spectroscopic methods with three primary objectives: (i) providing a comprehensive understanding of modern NMR and optical spectroscopic techniques used in university research laboratories and centers; (ii) equipping students with theoretical knowledge to analyze NMR, infrared, UV-visible, fluorescence, and Raman spectra; and (iii) offering practical experience in these techniques. Throughout the course, students will delve into the principles, instrumentation, and analytical applications of various NMR and optical spectroscopies.

Key words: NMR, vibrational and optical spectroscopy, UV-vis, fluorescence, Infrared, Raman, surface-enhanced Raman spectroscopy

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basic knowledge in spectroscopy

Teaching methods and activities: Lectures (CM), Practical and Lab sessions (TD & TP)

Course Title: Strategies in organic synthesis

Course supervisor:

• G. Prestat

Goals: At the end of this course the student should be able to identify effective strategies for the synthesis of moderately complex organic compounds.

Description:

– Main protective groups in organic synthesis.
– Retrosynthesis elements: disconnection, building blocks, interconversion of functional groups, addition of functional groups. Examples of synthetic compounds of biological interest.

Key words: Organic synthesis ; Retrosynthetic analysis ; Protective groups

Total number of hours: 24  Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Mastery of basic knowledge and concept in organic chemistry.

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Heteroelements and heteroaromatics in organic chemistry

Course supervisor:

• G. Prestat & H. Dhimane

Goals: At the end of this course the student should be able to use the organic chemistry associated with  heteroelements for functional group interconversion, bond formation,  as well the syntheses and reactivities of heteroaromatic compounds.

Description: 

– Heteroelement for C-C and C-Het bond formation : Phosphorus: Arbusov, preparation of phosphonium salts, Wittig, Wittig-Horner, Mitsunobu, Corey-Fuchs … Sulfur: thioacetals, sulfonium and sulfoxonium ylides, beta anion, preparation and reactivity of sulfones, sulfoxides … Silicon: synthesis and reactivity of silyl enol ethers, Peterson olefination, trialkylsilyl diazomethane …

– Heteroaromatic Chemistry: Heterocycles constitutes the vast majority of all known organic compounds, and are key components of pharmaceuticals, agrochemical, electro-active polymers, flavorings… They are also found in many biologically significant natural products. This part of the module aims to provide an introduction to aromatic heterocycles by examining the properties, the reactivity patterns, and some important synthetic methods of the main monocyclic heteroaromatic compounds, including:

– Electron-rich aromatic heterocycles (pyrroles, furans, thiophenes, diazoles)

– Electron-deficient aromatic nitrogen heterocycles (pyridines, diazines)

On completion of this course you will be able to devise synthetic pathways to the above heteroaromatics from simple precursors, and suggest reagents and conditions for achieving their region-selective substitution.

Key words: Organic synthesis ; Phosphorus ; Sulfur ; Silicon ; heteroaromatic, cyclization/cyclocondensation, cycloaddition

Total number of hours: 24  Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Mastery of basic knowledge and concepts in organic chemistry.

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Chemistry of biomolecules

Course supervisor:

• M. Ethève-Quelquejeu

Goals: Biomolecules including proteins, carbohydrates, lipids, and nucleic acids are an important element of living organisms. Currently, these molecules offer tremendous potential for biotechnology, new therapeutic strategies, or synthetic biology. Many pharmaceutical companies and academic groups are entering or investing in this field, and the chemists have already played a major role in all of these developments.

The aim of this course is to address the specific problems for the synthesis of biomolecules (peptides, sugars, and nucleic acids) based on general notions of organic chemistry.

Description: 

Sugars: Structural aspects (conformation,), monosaccharide chemistry (protective groups), formation of the O-glycosidic bonds (methods of activation, control of stereochemistry, mechanistic aspects).

Peptides: Formation of peptide bonds, strategy of synthesis, synthesis on solid support.

Nucleic acids: Protective groups, Phosphodiester bond formation, solid support synthesis.

Key words: peptides, sugars and nucleic acids chemistry

Total number of hours: 24  Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basis in organic chemistry and molecular biochemistry  .

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Biological Chemistry

Course supervisor:

• B. Colasson

Goals: This class will describe at the molecular level some principles governing the reactivity in enzymes and metallo-enzymes for different class of reactions (hydrolytic catalysis, redox catalysis) involved in different metabolic pathways. The focus will be made on the reaction mechanisms at the active sites.

Description: 

# bioinorganic chemistry in a biological context:

1- Presentation of the bio-inorganic domain

2. Hydrolytic processes (hydrolysis of peptides)
3. Redox reactions and dioxygen activation

# bioorganic chemistry in a biological context:

1- Reaction mechanisms in bioorganic chemistry

2. Metabolism of aminoacids
3. Metabolism of carbohydrates
4. Metabolism of nucleotides

Key words: enzymatic catalysis – bioorganic reactions – bioinorganic reactions

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: knowledge and basic concepts in chemistry (organic and coordination chemistry, acid-base catalysis, redox reactions) and biochemistry (amino acids, proteins, enzymes, active site) from Bachelor’s degree

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: heterogeneous and enzymatic catalysis

Course supervisor:

• V. Balland

Goals: This course will examine catalysis from the angle of both mechanisms and kinetics. An introductory course will review the basics of kinetics, in particular the theory of the activated complex, but also the influence of mass transport and of some environmental conditions (temperature, viscosity, ionic strength).

Description: The course will then be divided into sequences, dealing successively with homogeneous catalysis (mainly enzymatic and organometallic), (II) heterogeneous catalysis, and (III) an introduction to the concepts of photo- and electrocatalysis. The different types of catalysis will be illustrated using emblematic concrete examples, which will enable students to broaden their scientific knowledge in a variety of fields of application. Particular care will be taken not only to carry out a rigorous kinetic analysis but also to highlight the structure-performance relationship of the catalysts studied. This course is therefore aimed at students wishing to follow the Chemistry for Energies or the ChemBiotech pathways.

Key words: catalytic mechanism, reaction rate, rate determining step, selectivity

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Undergraduate level in physical chemistry (basis of kinetics) and inorganic chemistry

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Chemistry of Materials

Course supervisor:

• L. Sicard

Goals: This course aims to give to students the necessary skills and knowledge on materials they will encounter for different applications in the field of energy.

Description: Different families of materials will be described in relation to their types of chemical bonds. Specifically, metals, metal oxides (and ceramics in general), and polymers will be studied. For polymers, their thermomechanical properties will be briefly discussed, allowing their classification into thermoplastics, elastomers, and thermosettings. The successive lectures, associated with tutorials, will cover the properties of these several families of materials and the associated methods for characterizing them, enabling the determination of relevant physical properties.

In a second part, the course will be dedicated to an in-depth study of the fundamental principles and mechanisms of electrical conduction in solid materials, as modeled by various theoretical frameworks (free electron gas/Sommerfeld model, energy band theory, and Bloch theorem). Special attention will be given to the influence of defects and doping on their electrical and optical properties.

Key words: materials, polymers, metals, oxides, ceramics

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basis of solid chemistry, crystallography

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

 backgroundCourse Title: Introduction of Electrochemistry

Course supervisor:

• V. Noel

Goals: This course aims to introduce the key fundamental concepts required to understand and study the heterogeneous processes occurring at a charged interface. This knowledge is necessary for the R&D of major fields of application such as (electro)synthesis, and energy conversion.

Description: The content is divided into two main parts, each of them containing lectures and tutorials. Parti 1 (Lecture 6h, Tutorial 6h) Kinetic and thermodynamic modeling of electron transfers reactions. The different processes associated to charge transfer reactions to an electrode, as well as the way to study them, will be detailed. The course will provide students with solid theoretical skills in the following topics: Thermodynamics and kinetics of an electrochemical cell; Solution transport processes; Modeling electrochemical reactions. Part 2 (Lecture 6h, Tutorial 4h): From theory to supercapacitor : The purpose of this second part is to give the key fundamental concept underlying the current energy storage technologies. Students will acquire the following basic skills: Basics of Debye-Hückel theory for electrolyte solutions: Apply concepts to explain the behavior of ions in solution. Use the Debye-Hückel equations to calculate the electrostatic potentials and activity coefficients of the ions. Electrical double layer and its role in supercapacitors. Study the formation mechanisms and theoretical models of the electric double layer. Apply these concepts to the modeling of supercapacitors.

Keywords: Electrochemistry, charged interface, transport in solution

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: chemistry bachelor

Teaching methods and activities: lectures (CM), practical sessions (TD)

Course Title: Surface chemistry

Course supervisor:

• B. Schollhorn

Goals: This Teaching Unit provides the students with the fundamentals of surface functionalization both from a physical and a
chemical point of view.

Description: This Teaching Unit is divided in two parts, providing the fundamentals of surface chemistry. The first part (12 h) describes the basic concepts of chemistry and physics of surfaces and interfaces. In particular, this course aims at delivering fundamental knowledge in thermodynamics of interfaces, introducing surface tension, contact angle and wetting phenomena, to name a few. An important part of the course will be dedicated on physi- and chemi-sorption and the different classical models allowing to determine the specific surface area as well as to gain information on the porosity of the materials. The different concepts covered in class will be illustrated through exercises and problems. The second part (12 h) deals with chemical functionalization methods. Self-assembly processes and chemisorption for the formation of molecular monolayers will be described as well as the elaboration of thin layers via post-functionalization of self-assembled monolayers or direct electrografting of small molecules up to conducting polymers.

Keywords: surface energy, surface characterization, physi/chemisorption, surface functionalization, self-assembled monolayers, electrografting

Total number of hours: 24    Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed:  Bachelor level: in thermodynamics, kinetics and crystallography – chemical reactivity in organic and inorganic chemistry – basics of spectroscopy and electrochemistry

Teaching methods and activities: lectures (CM)   practical sessions (TD)

Course Title: Coordination Chemistry

(mandatory for ChemHealth track)

Course supervisor:

• D. Over

Goals: This module is intended as a master level course covering transition metal and coordination chemistry. The aim is to provide an overview in bonding and spectroscopy, as well as an understanding of the reactivity of coordination compounds.

Description: 

– Bonding (molecular orbital theory and crystal field), spectroscopy, magnetism
– Photochemistry, redox- and substitution reactions

Acquired skills: In the end of this course, a student should be able to fully understand the chemistry of the d-elements and be able to rationalize the trends of their chemical properties across the periodic table. With these tools in hand, a student should be able to interpret electronic and IR spectra, and to design synthetic strategies for coordination compounds as well as to evaluate their reactivity.
Key words: Coordination chemistry, transition metals, spectroscopy, magnetism, reactivity

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: General, inorganic and organic chemistry acquired in the Bachelor program.

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: Final written exam. Depending on the number of the students, a presentation of scientific papers will be asked.

Course Title: Basis of Computational chemistry

(Mandatory for AI track)

Course supervisor:

• E. Bremond & A. Perrier

Goals: The course will provide to the students the fundamental knowledge in computational chemistry methods. At the end of this lecture, the students should know how to use quantum chemistry concepts at the appropriate level of theory to undertake a computational chemistry study. They will also be able to determine the geometry and electronic properties of organic molecules using a quantum chemistry software.

Description: The first part of the lecture will be dedicated to the fundamentals of electronic structure calculations (lectures 12h): (1) Introduction to the quantum many-electron problem, (2) Hartree-Fock (HF) method, (3) Overview of post-HF methods for electron correlation, and (4) Density Functional Theory (DFT). The second part of the lecture  will be dedicated to practicals (12h) with a series of hands-on problems: (1) SCF-LCAO calculation of the ground electronic state of the helium atom,  (2) Fundamentals of the characterization of Potential Energy Surfaces (optimization, characterization of transition states, dissociation), (3) Electronic structure of p-conjugated organic molecules: analysis of electron density, inductive and mesomeric effects, atomic partial charge.

 Key words: Hartree-Fock ; Density-Functional Theory; Potential Energy Surfaces; Electronic structures, Quantum chemistry software

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Undergraduate level in chemical bonding and quantum chemistry (wavefunction, atomic and molecular orbitals)

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Physico-chemistry of biomolecular interactions

(Mandatory for ChemBiotech track)

Course supervisor:

• F. Mavré

Goals: This teaching addresses the topic of biomolecular recognition between simple biomolecules (nucleic acids, proteins) and ligands.

Description: After reviewing the composition and structure of the biomolecules, and the range of weak interactions at work, we will modelize and analyze the ligand binding phenomenon from a generic point of view and introduce a number of suitable experimental techniques for characterizing the thermodynamics and kinetics of the interaction. We will then look at biomolecular recognition with specific biomolecules (DNA, RNA, globular or membrane proteins) through a number of case studies, which will gradually increase in complexity. The objective of this teaching is to approach the structure/function relationships of simple biomolecules from the physico-chemist’s point of view, for instance by understanding how interactions of biomolecules with natural or synthetic molecules can alter their function and how this can be quantitatively described. This course will allow students to transpose classical physicochemical concepts to biomolecules; to analyse biomolecular ligand binding processes by considering weak interactions and the associated kinetic and thermodynamic aspects; and to reinforce their general biochemistry knowledge through case studies.

Key words: Ligand-binding, binding mechanisms, cooperativity, selectivity

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Undergraduate level in physical chemistry (basis of kinetics and thermodynamics)

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: Supramolecular chemistry and soft matter

Course supervisor:

• B. Colasson

Goals: The course will provide the students with basic and fundamental knowledge in supramolecular chemistry, from molecules in solution to self-assembled materials, while also introducing key concepts and cutting-edge applications of gels and colloids. The objectives are to give a wide overview of the use of non-covalent and covalent interactions in chemistry and to create connections for the design and analysis of systems at the molecular and macroscopic scales.

Description:  The course will cover the following items:

• Supramolecular chemistry
  

– Applications of supramolecular chemistry
– Historical background
– Definitions and concepts
– Non covalent interactions
– Self-assembly for molecular complexity and emergent properties
– Host-guest chemistry
– Molecular devices
– Self-assembly of simple molecules: from nano- to supramolecular structures

• Soft matter, gels and colloids
  

– Soft matter materials from biological or biologically inspired polymers
– Chemical and physical gels, their properties and swelling behavior
– Stimuli responsiveness of gels for different applications
– Coordination polymers
– Colloids
– From eco-design, lifespan to recycling

Key words: non covalent interactions, self-assembly, host-guest chemistry, gels, biological and smart polymers, colloids

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: A general background in chemistry (Bachelor’s degree) is required to attend to this UE.

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Course Title: PhD track

(Selective option)

Course supervisor:

• V. Noel

Goals: Immersion in a Laboratory Team with an international collaborative research project

Description: Selected student will have one day per week to work in the Team’s lab concerning the research project defined at the beginning with the consortium. the student will do his first intership (MA, 2 month) in the international partner laboratory and the second intership (M2, 6 months) in the local partner laboratory.

Acquired skills: 

Key words:

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Knowledge and basic concepts in chemistry (organic and coordination, acid-base catalysis, redox reactions) and biochemistry (amino acids, proteins, enzymes, active site, Michaelis–Menten)

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: Final exam 100 %

Course Title: Innovative track

(Selective option)

Course supervisor:

• V. Noel

Goals: 

Description: 

Acquired skills: 

Key words:

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Knowledge and basic concepts in chemistry (organic and coordination, acid-base catalysis, redox reactions) and biochemistry (amino acids, proteins, enzymes, active site, Michaelis–Menten)

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: Final exam 100 %

Course Title: Molecule and surface characterization II

Course supervisor:

• P. Martin

Goals: The objective of this teaching unit is to acquire basic knowledge of analytical chemistry methods for molecules and materials.

Description: The objective of this teaching unit is to acquire basic knowledge of analytical chemistry methods for molecules and materials. The course is divided into 2 chapters:
(A) Chromatography and Mass spectroscopy (9h): This chapter aims in particular to: i) Know the basic principle of GC & MS; ii) Know the different technical devices; Understand the operation and characteristics of the different types of GC & MS instruments (column, detectors, ionization sources, mass analyzers); ii) Exploit in detail a GC & MS spectrum of different types of molecules; iii) Choose the most suitable GC & MS method depending on whether the analysis is targeting a “small” organic molecule or a macromolecule (e.g. protein) with a study of the related applications. Recent developments allow coupling to separation methods for the analysis of complex samples (GC/MS, HPLC/MS)
(B) Interaction of radiation with matter: In this chapter, we will focus mainly on electrons and X-rays. (1) We will describe the different types of phenomena that occur: scattering, absorption, diffraction,..etc (8h)
(2) X-ray diffraction will then be developed. The principle of the technique will be outlined, as well as the information that can be obtained by reading a diffractogram. (7h)

Key words: Spectrometry, Mass Spectrometry, X-Ray diffraction, Transmission electronic microscope

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basic knowledge of separation methods (chromatography), spectroscopy and other analytical methods; as seen in bachelor

Teaching methods and activities: lectures (CM)  practical sessions (TD)

Course Title: Tutored project

Course supervisor:

• F. Berhal & S.Zrig

Goals: This course addresses numerous research topics in chemistry (medicine, materials, catalysis, energy…) and aims to introduce students to the management of a collaborative research project.

Description:  The training sequence encompasses (i) the bibliographic review, (ii) the design of a work plan, (iii) the experimental work and (iv) the synthesis of the results. Targeted skills: bibliographic search tools; redaction of scientific articles; teamwork; interdisciplinary; project management, experiments, characterization, and data analysis.

Key words: Organic synthesis, organometallic synthesis, physicochemical characterization

Total number of hours: 24     Number of ECTS: 3     Semester 2

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: First semester of the Master in Chemistry and Bachelor in Chemistry: Organic synthesis, physicochemistry, analytical chemistry.

Teaching methods and activities: Lectures (CM), Practical sessions (TD), Lab sessions (TP)

Course Title: Organometallic Chemistry

Course supervisor:

• H. Dhimane & G. Prestat

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: From bonding to catalysis

Course supervisor:

• G. Prestat

Goals: This transition-metal catalysis course in homogeneous phase allows students to acquire mastery of basic concepts of this field. Particular emphasis is placed on the understanding of reaction mechanisms and metal-ligand interactions in order to determine the optimal reaction conditions. Heck reactions, palladium-catalyzed cross-couplings and olefin metathesis are studied in depth.

Description: 
Coordination chemistry for organometallic catalysis
Elementary coordination chemistry: M-C and M-H bonds
Phosphine ligands, NHC carbene ligands
Pi-ligands: cyclopentadienyl, allyl, alkene, alkyne …
Elementary steps in organometallic chemistry: oxidative addition and reductive elimination, insertion and disinsertion, electrophilic and nucleophilic attack …
The general concept of catalysis and examples of the use of organometallic compounds in homogeneous catalysis: C-C couplings, Wacker process, olefin metathesis.
Organometallic catalysis
Mizoroki-Heck Coupling: Mechanism – regioselectivity – reactivity of halogenated and pseudo-halogenated partners – ligandless conditions – cyclizations – stereochemical aspects and asymmetric versions.
Cross-Couplings: Mechanistic aspects – Kumadu-Corriu – Negishi – Stille – Suzuki-Miyaura – Hiyama – Sonogashira
Olefin metathesis
Pd-catalyzed Allylic Alkylation

Acquired skills: Mastery of metal-ligand sigma and pi interactions and elementary steps in organometallic chemistry. Understanding of basic organometallic catalysis concepts in homogeneous phase. Mastery of palladium-catalyzed couplings and olefin metathesis.

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Mastery of basic knowledge and concepts in inorganic and organic chemistry acquired L3 chemistry.

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: Final written exam (100 %)

Course Title: Orbitals, reactivity, mechanisms

Course supervisor:

• H. Dhimane & F. Berhal

Goals: 

Description:  The first part of this course gives a brief presentation of molecular orbital theory (Hückel for conjugated p-systems) then addresses pericyclic reactions and different methods (Dewar-Zimmermann, Woodward-Hofmann rules and Fukui’s method) used to rationalize many aspects of these reactions. The second part is dedicated to stereoelectronic effects and their importance in explaining the molecular shape, conformation, stability, reactivity and selectivity. The last part addresses the reaction mechanism determination aiming to prepare you to (1) elucidate the mechanism of chemical reactions based on kinetic and thermodynamic principles and collected data, and (2) be able to evaluate mechanistic arguments made in the literature.

Acquired skills: 

Key words: Molecular orbitals, pericyclic reactions, stereoelectronic effects, conformational analysis, reaction mechanisms.

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Nuclear magnetic resonance

Course supervisor:

• N. Giraud

Goals: This lecture will introduce the main features of NMR pulse sequences.

Description:  A simplified theoretical formalism will be developed to describe and understand the evolution of macroscopic nuclear magnetization during the NMR experiment. The fundamental concept of multi-dimensional NMR will be introduced. Heteronuclear NMR will be addressed: the sensitivity and the quality of the data that are available for a selection of heteronuclei in the field of organic chemistry will be discussed. Finally, nuclear spin relaxation will be introduced, and its application to the determination of molecular dynamics and self-diffusion processes will be described. Tutorials will allow for completing theoretical concepts with exercises focused on applications. A practical session will allow students for applying the acquired knowledge to the acquisition of data targeting dynamic and/or structural analysis. Basis of solid-State NMR will also be introduced.

Content:

Pulsed NMR and Fourier Transform

• Magnetic Resonance Phenomenon
• What Do We Detect in NMR Spectroscopy?
• The NMR Spectrometer
• Pulsed NMR

Multi-dimensional NMR

• Principle of Multi-Dimensional NMR
• Implementation of a 2D NMR Experiment
• Analytical Strategies in 2D NMR

Relaxation

• Principle of Nuclear Relaxation
• Cross Relaxation

Introduction to Solid-State NMR

Acquired skills: 

Key words: 1D and 2D NMR pulse sequences, nuclear spin relaxation, nuclear Overhauser effect (nOe), diffusion, dynamics and structural analysis

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Fundamentals of NMR: magnetic properties of the nucleus, Zeeman effect, chemical shift, scalar spin-spin coupling. Dynamic process in molecular samples

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Lab skills – Molecular Chemistry

Course supervisor:

• P. Busca

Goals: 

Description: Lab skills is a series of practicals scheduled for the same week, to give you an idea of what it’s like to spend a week in a research lab.  The aim of this course is to brush up on the basics and learn more advanced techniques (set up of reactions under argon, the use of a vacuum ramp, management of syringe injections) so as to be ready for the internship. The program includes the multi-step synthesis of a ligand L and it’s use in a palladium-catalyzed cross coupling. To do so, the schedule is as follows: 

• Monday (all day): Synthesis of the first intermediate
• Tuesday (morning): Synthesis of the second intermediate and launch the preparation of L (writing in the afternoon)
• Wednesday (all day): purification of L and launch the cross-coupling
• Thursday (morning): NMR analysis of reaction mixture and pooling of results (writing in the afternoon)
• Friday: final analyses, writing and sending reports

Acquired skills: 

Key words: lab skills, multi-step synthesis, organometallic catalysis

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Surfaces and biosensing

Course supervisor:

• B. Piro

Goals: This teaching addresses the topics of biosensing and biomolecular diagnostics.

Description: 

The main challenge in biosensing and biomolecular diagnostic is to selectively reveal the reaction of the targeted molecule with a sensing unit (an immunoreaction, a DNA hybridization, an enzyme/substrate reaction…) and then translate it into an appropriate readout (electrical signal, optical signal …). This can either involve homogenous (bio)-chemical reactions or more complex interfacial chemistry. This course will describe how the choice of sensing bioreceptor and transduction mode impact the analytical performances. The physico-chemical concept of surface chemistry, methods of surface modifications and their application for biosensing will be addressed. This course will also allow students to better understand the influence of thermodynamic and kinetic parameters of the surface biorecognition on the analytical performances of biosensors and immunoassays.

The course will be divided in the following sequences:

• General concepts of biosensing (4 hrs CM + 2hrs TD)
• Surface modification of sensing interfaces (2 hrs CM)
• Immunoassays (4 hrs CM)
• Kinetics and thermodynamics of biomolecular recognition on surfaces (2 hrs CM + 4hrs TD)
• Cases studies (4 hrs of tutoring)
• Seminar by a professional (industrial applications, reglementation)

Acquired skills: 

Key words: biomolecular diagnostics, Surface modification, Enzymatic biosensors

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Notions in structure of biomolecules

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Optical spectroscopic methods for biomolecules analysis

Course supervisor:

• N. Felidj

Goals: Interactions between biomolecules (protein, DNA, etc.) play a fundamental role in signaling pathways that regulate numerous cell functions.  Study of these interactions makes it possible to understand the biological mechanisms and the physiopathology of many human diseases (cancer, neuro-degenerative illnesses).

Description: Their understanding thus offers possibilities for therapeutic intervention, by developing interface inhibitors, often more specific that inhibitors of enzymatic activity.  After defining the characteristics of interactions between biomolecules (thermodynamic, kinetic, etc.) by presenting the structural and functional properties of these interfaces, we shall study physicochemical and analytical methods and techniques to detect these interactions, such as: Surface Plasmon Resonance imaging (SPRi), Fluorescence, Raman, Infrared (IR) and Circular Dichroism (CD) spectroscopies. This course will primarily focus on the analysis of biomolecules and their interactions, building on the fundamental spectroscopic techniques taught in the first semester’s ‘Molecule and Surface Characterization I’ module. We will illustrate the different parts of the lecture with various examples, and with article presentations performed by the students.

Content:

– Thermodynamic and kinetic aspects of biomolecule interactions.

– IR spectroscopy for biomolecule analysis: IR signatures of biomolecules, analysis of protein secondary structure and flexibility. Difference IR spectroscopy: principle and examples of application, nano-IR spectroscopy and imaging.

– Circular dichroism (CD): UV-Vis signatures of biomolecules, definition and principle of CD, applications of CD to biomolecules and limitations.

– Fluorescence emission spectroscopy and microscopy for biomolecule analysis.

– Surface Plasmon Resonance (SPR): basics on surface plasmon propagation, excitation conditions, principle of the SPR technique, instrumentation.

– SPR imaging (SPRi) for biomolecule interactions.

– Raman spectroscopy: application for biomolecule analysis.

– Comparison of the various techniques.

Acquired skills: 

Key words: Surface plasmon resonance, IR, Raman, biosensors, fluorescence, circular dichroism

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Physicochemistry of nanoobjects

Course supervisor:

• D. Onidas

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Lab skills – Biotechnologies

Course supervisor:

• A. Mellet

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final exam

Course Title: Computational chemistry II

Course supervisor:

• A. Monari & F. Barbault

Goals: This module aims to provide the students with advanced concepts in numerical and data driven chemistry which are necessary in advanced molecular modeling and simulation. In particular the module will cover the formalisms and applications of density functional theory (DFT) including the performance and systematic improvement of exchange correlation functionals. 

Description: The molecular environment will be taken into account both implicitly with continuum methods and explicitly by hybrid quantum mechanics/molecular mechanics frameworks. The principle of classical and ab initio MD simulation will be also tackled with a special emphasis on the inference of structural and electronics properties from simulation trajectory, using also artificial intelligence based techniques for the reduction of dimensionality 

– Introduction to DFT theory et Kohn-Sham approximation
– Definition of Exchange Correlation functionals and their systematic improvement (Jakob Ladder)
– Modeling solvation through implicit polarizable continuum methods,
– Describing the environment using hybrid QM/MM methods. Electrostatic and polarizable effects and QM/MM frontier
– Molecular dynamics simulations in complex systems
– Analysis of trajectories, unsupervised artificial intelligence for clustering and identification of collective movements.

Acquired skills: 

Key words: Molecular modeling and simulation, DFT, QM/MM

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Computational Chemistry 1

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Artificial intelligence for chemists

Course supervisor:

• E. Bremond & F. Barbault

Goals: This course positions itself in the following of the Chemistry and Data Sciences lectures (Semester 1 — M1). It aims to familiarize students with the fundamental principles of artificial intelligence (AI) and its specific application to chemistry. 

Description: It explores basic AI concepts, focusing on machine learning (supervised and unsupervised) (lectures 6h). All the concepts covered will be illustrated through practical sessions primarily applying to various fields of chemistry (practical sessions 18h). The program includes:

– Introduction to AI, Data Types and their Representation
– Supervised AI Methods (Regressions, Random Forest, SVM…)
– Unsupervised Learning and Clustering (k-means)
– Neural Networks and Deep Learning (dense to convolutional, image analysis…)
– Graph Neural Networks (GNN): Describe a molecule as a social network!
– Interpretability, Robustness and Ethics.  

Acquired skills: 

Key words: 

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Multiphysics modeling

Course supervisor:

• N. Challab

Goals: In Physics and chemistry, many phenomena can be described through differential equations such as heat transfer, chemical reactions, mass transport, electrostatic potential, Schrodinger equation, etc. Differential equations are however difficult or even impossible to solve using analytical equations.

The goal of this course is then to introduce students to the Finite Element Method (FEM) enabling to solve partial differential equations by dividing a complex chemical system into many smaller and simpler sub-units.

Description: Students will learn how to build a Multiphysics model and to further use it to study different configurations and operating conditions or to predict macroscale physical and chemical properties. Through several chemically-relevant examples, students will learn how to make modeling assumptions, how to discretize the space by defining system geometry, mesh and nodes, to apply relevant boundary conditions and to display, assess and interpret the relevance of the collected results.

The course will include modeling the transport of chemical species in solution, homogeneous and heterogeneous reaction processes and charged interfaces.

Multiphysics models are also relevant for studying the magnetic properties of materials, in electrochemistry, in optics, etc.  

Acquired skills: 

Key words: 

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Lab skills – Molecular or multiphysics modeling

Course supervisor:

• A. Perrier

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Physicochemistry of semiconductors

Course supervisor:

• N. Battaglini

Goals: The purpose is to introduce electronic transport properties of organic and inorganic semiconductors as well as the basic principles of semiconductor-based devices. 

Description: The course contents is the following: Part 1 – band structure of semiconductors (direct versus indirect bandgap), density of states, notion of hole, density of charge carriers, intrinsic and extrinsic semiconductors (doping and temperature effects); electronic transport (Drude model: conductivity, mobility of charge carriers), drift current under electric field versus diffusion current under gradient of concentration, polarizability (delocalized transport versus hoping), out-of-equilibrium semiconductor (generation/recombination processes of charge carriers). Part 2 – Inorganic PN junction (Schockley equation), organic Schottky diode (metal/organic semiconductor interface), optical properties of organic and inorganic semiconductors (light absorption, photoluminescence and electroluminescence), basic operation of  optoelectronic devices (photodiode, photovoltaic diode, electroluminescent diode. 

Acquired skills: 

Key words: electronic properties; doping; conductivity; pn junction; Schottky diode; optoelectronic devices

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: wave/particle duality; pi-conjugated system; cubic crystal lattice in direct and reciprocal space; electron diffraction by crystal lattice; free electron gas (Sommerfeld model: electron energy quantization, standing electronic waves in the crystal, periodic boundary conditions); wave function of electron in periodic potential (Bloch theorem); theory of energy bands (Fermi surface, Brillouin zones, bandgap, density of states of 1D, 2D, 3D crystals) ; perfect Fermi gas (Fermi-Dirac statistics).

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Macro- to nanostructuration of surfaces

Course supervisor:

• G. Mattana

Goals: 

Description: This teaching unit is an introductory course on surface structuration. The topics treated during the TU are as follows:

i) reminders on surface properties (surface roughness and energy) (2 hours)

ii) surface modification by physical methods: from deposition methods (thermal evaporation, spin-coating), etching/functionalization methods (plasma techniques) to photolithography techniques (7 hours);

iii) surface modification by chemical methods: from the gas phase: Chemical Vapour Deposition (CVD), Atomic Layer Deposition (ALD), or from solution phase: self-assembled monolayers, electrochemical methods (electrografting, electrodeposition, electropolymerization) (8 hours).

iv) Printing deposition techniques: definition, process and applications; inks and substrates properties and interaction, examples of printing techniques (inkjet, screen-printing, capillary printing). Examples and applications of surface structuration by printing (7 hours).

 Acquired skills: 

Key words: Surface modification, surface structure, physical and chemical deposition methods, photolithography

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Basic knowledge on surface properties

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Inorganic nanomaterials: from fundamentals to practice

Course supervisor:

• J.-Y. Piquemal

Goals: This course aims to provide fundamental knowledge on the creation of both inorganic and organic nanomaterials. It is divided into two parts: the first focuses on the development of inorganic nanomaterials using soft chemistry tools following bottom-up approaches, while the second is dedicated to the preparation of organic nanoparticles such as liposomes and polymers.

Description: For inorganic nanomaterials, theoretical aspects governing their formation and stabilization will be presented initially, offering a comprehensive overview of various strategies for preparing metals, oxides, and semiconductors at the nanoscale. Several techniques used for the study of these nanomaterials will be introduced and described such as X-ray diffraction, X-Ray photoelectron spectroscopy, electronic microscopy, nitrogen adsorption, thermogravimetric analysis and differential scanning calorimetry, to name a few.

Regarding organic nanomaterials, the course will first introduce the different families of organic nanoparticles and the methods used to synthesize them. Following this, examples of their applications in nanomedicine and environmental fields will be discussed.

To reinforce the knowledge delivered in the main lectures, students will engage with various problems and exercises. Additionally, students will have the opportunity to apply the concepts presented in the course through hands-on laboratory sessions.

Acquired skills: 

Key words:  Inorganic and organic nanomaterials, elaboration, supra-molecular chemistry, top-down and bottom-up approaches, bio-nanotechnologies, nanomaterials characterization techniques

Total number of hours: 24     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: B. Sc. level in organic chemistry, thermodynamics, crystallography and kinetics

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Lab skills – Electrochemical methodologies

Course supervisor:

• P. Martin

Goals: 

Description:  This lab work sessions will focus on the use of various electrochemical techniques for the characterization and the analysis of electrochemical reactions and electrocatalytic processes. During five lab sessions (6h) several projects will be addressed: from a molecular point of view with the study of redox probes behaviors in solution to the analysis of inorganic materials for energy storage or conversion.
Each session is composed of a short introduction (1-2h) describing the different technics used during the lab session. Then the student (group of two) should investigate the synthesis/modification of materials/electrode, the properties of functional organic/inorganic layers using various electrochemical technics (from the cyclic voltammetry to the tafel plot).
A report for each session will be done and an oral defense of one subject will be done by each student.

Acquired skills: 

Key words: 

Total number of hours: 30     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: UE “ Basis of Electrochemistry “

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Green chemistry project

Course supervisor:

• P. Busca

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Artificial Intelligence for chemists & Research Seminar

Course supervisor:

• A. Monari & B. Schöllhorn

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Collaborative research project – Part 1

Course supervisor:

• V. Noel

Goals: The aim is to introduce Master 2 students to research projects and to strengthen their soft skills related to collaborative work.

Description: 

This course will be divided into two parts. The first part will be taught under a classical form (lectures, seminars) allowing students to acquire the necessary knowledge to successfully carry out the second part, were they will be asked to work independently to build their own collaborative research project.

Part 1: In an initial stage, the main research funding agencies (public and private) will be presented; the structure and management of collaborative research projects (timetables, milestones, deliverables…) will be also described. Several scientific experts will give seminars allowing grasping the contemporary trends and stakes of the discipline (chemistry and big data, the chemical industry 2.0, the chemistry at the interfaces…).

Part 2: In a second phase, students will be divided into groups of 3 to 4 people constituting a team. Several teams will be associated to form a consortium whose mission is to build a collaborative research project of a European type (FET-OPEN or RIA). Each consortium will have to structure, budget and justify its project using the planning tools and the ad-hoc methods.

Acquired skills: 

• Analysis and summary skills of the scientific production in a given field (publications, patents)
• Ability to develop a creative approach to solve a scientific problem
• Team building, Integration into a working team and ability to be a source of propositions
• Capacity to present the results under different forms (oral presentations, written reports…)

Number of ECTS: 3     Semester 3

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: M1

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 

Course Title: Chemistry of RNA, DNA and proteins for new therapeutic strategies

Course supervisor:

• M. Ethève-Quelquejeu

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Chemical biology

Course supervisor:

• P. Busca

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Selective methods for medicinal chemistry

Course supervisor:

• G. Prestat

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: NMR of biomolecules: structure, dynamics and interactions

Course supervisor:

• N. Giraud

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Bio-inspired catalysis

Course supervisor:

• B. Colasson

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Nanomedicine

Course supervisor:

• M. Hemadi

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Biomolecular diagnotics and DNA technologies

Course supervisor:

• F. Mavré

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Bioimaging

Course supervisor:

• C. Mangeney

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Metabolomics

Course supervisor:

• N. Giraud

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Biomaterials and smart devices

Course supervisor:

• C. Mangeney

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Computational photochemistry

Course supervisor:

• A. Monari & F. Maurel

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Materials and nanomaterials modeling

Course supervisor:

• M. Seydou & A. Monari

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Modeling rare events

Course supervisor:

• A. Monari & F. Barbault

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Biomolecular modeling 

Course supervisor:

• A. Monari & F. Barbault

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: From charaterization to Big Data 

Course supervisor:

• J.-F. Lemineur

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Advanced electrochemistry 

Course supervisor:

• F. Mavré

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Electrochemical energy storage  

Course supervisor:

• V. Balland

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Photoconversion  

Course supervisor:

• N. Felidj

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Materials, catalysis, photocatalysis, Electrocatalysis  

Course supervisor:

• J. Peron

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Medicinal chemistry  

Course supervisor:

• P. Busca

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Medicinal chemistry  

Course supervisor:

• P. Busca

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Large instruments and Laboratory Platforms: Techniques and Applications  

Course supervisor:

• M. Giraud

Goals: 

Description: 

Acquired skills: 

Key words: 

Total number of hours: 20     Number of ECTS: 3     Semester 1

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: 

Teaching methods and activities: Lectures (CM), Practical sessions (TD)

Assessment: 100% Final written exam

Course Title: Collaborative research project Part II

Course supervisor:

• V. Noel

Goals: The aim is to introduce Master 2 students to project research and to strengthen their soft skills related to collaborative work.

Description: 
Ce cours s’inscrit dans la continuité de l’UE “Research Project 1”.
Students will be divided into groups of 3 to 4 people constituting a team. Several teams will be associated to form a consortium whose mission is to build a collaborative research project of a European type (FET-OPEN or RIA). Each consortium will have to defend its research project in front of a panel (students + teachers), i.e. to justify the project structure, budget, expected timetable as well as the scientific and technological proposed approaches.

Acquired skills: Communication skills such as articulating ideas, clarity and concision in argues description, public speaking…

Total number of hours: 24     Number of ECTS: 3     Semester 4

Mandatory course   ☒               Optional course   ☐

Prerequisites/skills needed: Research Project 1

Assessment: Examen Final (Oral Presentation) -100 %